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Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Required)

Department of Health and Human Services — National Institutes of Health

Award amount
Up to $375K
Deadline
Jan 7, 2027
Status
Open
Geography
Nationwide
Funding type
Federal Grant
Last verified
Oct 10, 2026
Program summary
The purpose of this Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions is to support small scale research grants at institutions that do not receive substantial funding from the NIH, with an emphasis on providing biomedical research experiences primarily for undergraduate students and enhancing the research environment at applicant institutions.Eligible institutions must award baccalaureate science degrees and have received no more than $6 million dollars per year of NIH support (in both direct and F and A/indirect costs) in 4 of the last 7 fiscal years. For institutions composed of multiple schools and colleges, the $6 million funding limit is based on the amount of NIH funding received by all the non-health professional schools and colleges within the institution as a whole.This Notice of Funding Opportunity (NOFO) supports investigator-initiated mechanistic and/or minimal risk clinical trials addressing the mission and research interests of the participating NIH institutes. For the purpose of this NOFO, minimal risk clinical trials are defined as those that do not require FDA oversight, do not intend to formally establish efficacy, and have low risks to potentially cause physical or psychological harm.
Eligibility as stated by the source
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs) ; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
How to apply
Apply through Grants.gov
Contact
National Institutes of Health · grantsinfo@nih.gov · 301-402-2541
Notes
Opportunity number PAR-24-214.

Before you can apply

Federal applications require an active SAM.gov entity registration (Unique Entity ID) and a Grants.gov account with an Authorized Organization Representative role. SAM.gov registration commonly takes 2 to 4 weeks, so start it well before the deadline.

  • SAM.gov entity registration (UEI) — typically Commonly 2 to 4 weeks · No feeFederal grant and contract applicants must hold an active registration in the System for Award Management, which issues the Unique Entity ID used on every federal application.Start this registration
  • Grants.gov account and role assignment — typically Commonly a few days after SAM.gov registration is active · No feeApplications submitted through Grants.gov require an individual account plus an Authorized Organization Representative role approved by your organization's e-Business Point of Contact.Start this registration
  • Employer Identification Number (EIN) — typically Same day when applied for online · No feeAn EIN identifies the applying business or organization on nearly every funding application.Start this registration
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Source and verification

Change history

  • Oct 2, 2026 — Discovered: open