Cancer Prevention and Control Clinical Trials Grant Program (R01 Clinical Trial Required)
Department of Health and Human Services — National Institutes of Health
- Program summary
- Through this notice of funding opportunity (NOFO), the National Cancer Institute (NCI) invites applications for support of investigator-initiated clinical trials that have the potential to reduce the burden of cancer through improvements in early detection, screening, prevention and interception, healthcare delivery, quality of life, and/or survivorship related to cancer; with such attributes, the proposed studies should also have the potential to improve clinical practice and/or public health. Applications submitted to this NOFO must include studies that meet the National Institutes of Health (NIH) definition of a clinical trial (see NOT-OD-15-015 for details) and provide specific clinical trial information as described in this FOA. This NOFO does not and will not support clinical trials for studies of cancer diagnosis and/or oncologic therapy in patients. The proposed investigator-initiated projects should be related to the programmatic interests of the NCI Division of Cancer Prevention and/or the NCI Division of Cancer Control and Population Sciences.
- Eligibility as stated by the source
- Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.
- How to apply
- Apply through Grants.gov
- Contact
- National Institutes of Health · grantsinfo@nih.gov · 301-402-2541
- Notes
- Opportunity number PAR-25-167.
Before you can apply
Federal applications require an active SAM.gov entity registration (Unique Entity ID) and a Grants.gov account with an Authorized Organization Representative role. SAM.gov registration commonly takes 2 to 4 weeks, so start it well before the deadline.
- SAM.gov entity registration (UEI) — typically Commonly 2 to 4 weeks · No feeFederal grant and contract applicants must hold an active registration in the System for Award Management, which issues the Unique Entity ID used on every federal application.Start this registration
- Grants.gov account and role assignment — typically Commonly a few days after SAM.gov registration is active · No feeApplications submitted through Grants.gov require an individual account plus an Authorized Organization Representative role approved by your organization's e-Business Point of Contact.Start this registration
- Employer Identification Number (EIN) — typically Same day when applied for online · No feeAn EIN identifies the applying business or organization on nearly every funding application.Start this registration
- IRS tax-exempt determination letter — typically Varies; already issued for established nonprofits · Application fee applies to new filingsNonprofit-restricted programs generally require a copy of the IRS determination letter recognizing tax-exempt status.Start this registration
Source and verification
- Primary source: http://grants.nih.gov/grants/guide/pa-files/PAR-25-167.html
- Source reference ID: 357074
- Some categories on this record were inferred from the program text rather than stated explicitly by the source.
Change history
- Sep 30, 2026 — Discovered: open